A new study revealed that the “Lorundrostat” is a safe and effective treatment for people with unspecified or remedial blood pressure, as blood pressure has decreased to a wide variety of patients who took it continuously.
Lorerdostat is prohibited to produce the hormone aldosterone. The hormone is known as a stereid hormone produced from the adrenal cortex (the outer layer of the adrenal gland), and helps in regulating the balance of water and salts in the kidneys by keeping sodium inside the body and removing potassium from it. High level of aldosterone can lead to high blood pressure and fluid accumulation in the body’s tissues.
The study was conducted by researchers from the William Harvey Heart Center at Queen Mary University in London, and high blood pressure specialists at the Bartus Health Foundation of the National Health Services Authority in the United Kingdom, and its results were announced at the thirty -fourth European meeting on high blood pressure and cardiovascular protection that was held during the period between 23 and 26 May this May, and the Yoric Alrt website was written about.
Patients participated in adult patients who did not achieve their goal by lowering blood pressure, despite taking 2 to 5 blood pressure.
Aldosterone and blood pressure
Dr. Manish Saxina, co -director of the William Harvey Heart Center at Queen Mary University in London and high blood pressure specialist at the Barts Health Foundation of the National Health Services Authority and the researcher participating in the study, stated that “despite the availability of treatments, more than 40% of adults with high blood pressure around the world do not achieve their goal of lowering blood pressure. Upper Egypt is a need to explore new treatments for high blood pressure Experience this need. “
Dr. Harvey explained that the aldosterone plays an important role in regulating blood pressure. He added that they tested the medicine on a large and varied group of patients around the world, and found that it had a good safety record, and has contributed to continuous lowering blood pressure in different groups of patients. Once it is commercially available, it may be a new treatment option for high blood pressure in millions of patients around the world.
High blood pressure affects one in three adults around the world, and increases the risk of heart disease, heart attacks and strokes.
30% of patients with high blood pressure suffer from an imbalance in the regulation of aldosterone, which means an imbalance of the body’s natural mechanism to control it. Increased aldosterone levels can lead to high blood pressure. Lorerdostat is designed to reduce aldosterone levels by inhibiting the enzyme responsible for its production.
The heart muscle contracts during its work and extends, and this leads to the blood pressure of two values, the first is called systolic blood pressure and recorded when the heart contracts, the second is diastolic pressure and is recorded when the (relaxation) of the heart muscle (relaxation). The dose of 50 mg of Lorundrostat once a day showed a noticeable and continuous decrease in systolic blood pressure.
